Rotenone is one of the oldest naturally occurring compounds present in a number of plants. To test effect of curcumin on rotenone toxicity, we used the lc 80 the concentration causing 80% cell death of rotenone. It is known that this interference of the electron transport chain occurs from complex i to ubiquinone, similarly to amytal. Characterize effects on target and nontarget organisms and environmental fate of rotenone under specific treatment conditions and communicate that to project.
Rotenone kills fish by inhibiting cellular respiration and the ability to use dissolved oxygen. Sdi20080306003 item nominal value remark nominal voltage 3. Pdf is a hugely popular format for documents simply because it is independent of the hardware or application used to create that file. Chemical list msds woods hole oceanographic institution.
Rotenone preparations are unstable in light and air. Jul 14, 2016 rotenone is highly toxic for aquatic organisms, but not for birds 2, 15. Nitrogen msds material safety data sheet for nitrogen n2 reference. Acute toxicity oral category 2 acute toxicity dermal category 2 skin corrosionirritation category 2 eye damageirritation category 2a. Epa, pesticide product label, prentox rotenone fish. Rotenone is used in home gardens for insect control, for lice and tick control on pets, and for fish eradications as part of water body management. In vitro, rotenone induces formation of micronuclei and modifies the microtubule organizing centers of mitotic spindles. Rotenone in ethanol 20mm snitrosonacetyldlpenicillamine snap sds 10 vol% sodium azide sodium bisulfite sodium hydroxide sodium molybdate sodium nitroprusside sodium selenite sulfuric acid 50% sybr green sytox green tae buffer 50x te buffer 100x 100ml thiamine. Curcumin protects against rotenoneinduced neurotoxicity. Product and company identification franklin international 2020 bruck street columbus oh 43207 12172010. It has a molecular formula of c 23 h 22 o 6 and a molecular weight 394. Read on to find out just how to combine multiple pdf files on macos and windows 10. Rotenone is a compound that occurs naturally in several plants and it has been used as abroad spectrum insecticide and pesticide. This requires that dust and spray mist be controlled as much as possible during application and that applicators and support staff be protected from inhalation risk.
See actual entry in rtecs for complete information. Safety data sheet issue date 06jun2018 revision date 15jul2019 revision number 5 1. However, we make no warranty of merchantibility or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Sigma brand products are sold through sigmaaldrich, inc. If your pdf reader is displaying an error instead of opening a pdf file, chances are that the file is c.
Some lake and river treatments have employed tonnes of rotenone without any significant effects on humans or wildlife. Section 1 chemical product and company identification. Sigmaaldrich 270970 page 1 of 7 sigmaaldrich material safety data sheet version 5. Formulation rotenone othercube resins other ingredients prentox prenfish 5% 10% 85% aromatic petroleum solventa cft legumine 5% 5% 90% inert ingredients, including n90 methylpyrrolidone chemfish 5% 5% 90% aromatic. Rotenone has been used on a vast scale in the united states over many decades. Index for rotenone pc code 071003 pesticides us epa. One of the fun things about computers is playing with programs like paint. Ac2370000, ac2370050, ac2370250, ac384300000, ac384300050, ac384300250 ac384300250 synonyms. Dec 21, 2016 safety data sheet dimethyl isosorbide date prepared. Identification product identification product identifier rotanium contax n.
Rotenone is classified as a class ii agent moderately hazardous by the who 2, 19. As in any fire, wear selfcontained breathing apparatus pressuredemand niosh approved or. February 11, 2014 page 2 of 7 carcinogenicity has been reported in animals, when all of the data are considered, the weight of evidence does not show that dgebpa is carcinogenic. Rotenone is the most toxic of the rotenoids followed by deguelin. Effects of rotenone on amphibians and macroinvertebrates. I paid for a pro membership specifically to enable this feature. Material safety data sheet west liberty university. Address date of revision print date chemtrec 24 hour. Planning and standard operating procedures for the use of rotenone in fish management. Just upload files you want to join together, reorder them with draganddrop if you need and click join files button to merge the documents. Table 1 presents the three chemical groups in case number 0255. Most electronic documents such as software manuals, hardware manuals and ebooks come in the pdf portable document format file format. Dust from machining the cured product may cause mechanical irritation of eyes, skin, nose, throat and upper respiratory tract.
Extoxnet primary files maintained and archived at oregon state university. Epa fact sheet national pollutant discharge elimination system npdes pdf this draft permit is being proposed to authorize point source discharges to waters of the united states u. Rotenone analysis by liquid chromatographytandem mass. North american suppliers of rotenone products for fish management. Rotenone has a low toxicity to pets and livestock generally but is very toxic to pigs.
No material contained in a lamp is released during normal use and operation. You can use the tools in paint to add something to a different document. Rotenone, cas 83794, agcn20516 is a synthetic high purity chemical. Upon project completion, the lake will be restocked with hatchery produced coho salmon andor rainbow trout.
Product company identification product identification samsung sdi lithiumion cellbattery samsung sdi sterlingplatinum sdi pn. The paint program can help you make new image files, but it cannot open document or pdf file. Adobe systems is a software manufacturer that has created many document and multimedia editing programs. Fish exposed to lethal rotenone concentrations move to the surface and gasp for oxygen as if the water was oxygendepleted. Rotenone cas 83794 calbiochem msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. Identification of the substancemixture and of the companyundertaking product name. Must be recovered in accordance with federal, state and local regulations. This means it can be viewed across multiple devices, regardless of the underlying operating system. Explain rotenone label and msds contents and requirements and how these affect use and protect human and environmental health of project personnel and the general public. Current rotenone environmental, public health, and regulatory. Toxicological information information on toxicological effects chemical name ld50 oral,ratmouse ld50 dermal,ratrabbit lc50 inhalation,ratmouse.
Acute toxicity oral category 2 acute toxicity dermal category 2. To combine pdf files into a single pdf document is easier than it looks. This article explains what pdfs are, how to open one, all the different ways. Safety data sheet 10042019 page 3 of 5 the summated ld50 is 50000 mgkg the summated ld50 is 11930 mgcubic meter. These plants are members of the pea leguminosae family. For rotenone toxicity doesresponse studies, shsy5y cells were added rotenone at 0 250 nm concentrations. The lethal doses of rotenone are 300500 mgkg for an adult, 143 mgkg for a child and 2 mgkg for rats 2, 10, 1618. Msds document numberhe000 revision dated 03 sept 96 in an emergency, call chemtrec at 8004249300 us toll free or 7035273887 contents. Adjuat pounda of rotenone according to the actual rotenone assay as noted under the ingredient statement on this label. Liquid rotenone pyrethrins spray concentrate controls insect pests, such as aphids, leafhoppers, japanese beetles, stink bugs, flea beetles. It occurs naturally in the seeds and stems of several plants, such as the jicama vine plant.
Chemicals and application of the proposed action specialist. Because of this, and because certifiers, farmers other people involved with organic production are still getting questions from the public about rotenone, board action is needed to clarify the situation by listing rotenone as a prohibited nonsynthetic. Rotenone is a pesticide that exhibits genotoxic, prooxidative, and neurodegenerative properties. Page 3 of 5 7 handling and storage precautions for safe handling. Safety data sheet rotronic humidity standards for north america. Rotenone investigated as a mutagen, reproductive effector, and tumorigen. Product and company identification product name dimethyl isosorbide cas number 5306854.
Preparation instructions this product is soluble in chloroform 50 mgml, yielding a clear yellow solution. Use on apples, plums, peas, squash, cabbage, oak, elm, cedar, petunia, aster, geranium, marigold. North american suppliers of rotenone products for fish. Rotenone blocks the mitochondrial electron transport chain through the inhibition of complex i, as seen in mptp.
A pdf portable document format is a widely popular type of document format created by adobe. Shop a large selection of terpene lactones products and learn more about rotenone, 97%, mp biomedicals. Rotenone products are classified as restricted use pesticides rup due to acute inhalation, acute oral, and aquatic toxicity. Pdf file or convert a pdf file to docx, jpg, or other file format. Rotenone is an inhibitor of mitochondrial electron transport at nicotinamide adenine dinucleotide nadh. Ingredients in chemical case 0255 pc code chemical name cas number 071001 derris resins other than rotenone 071003 rotenone 83794. The molecular formula of rotenone is c 23 h 22 o 6 with a molecular weight of 394. Jun 30, 2011 composition percent by weight of liquid rotenone formulations based on material safety data sheets msds. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals.
Operation of drip stations, peristaltic pumps and propwash venturi for application of liquid rotenone sop. Current rotenone environmental, public health, and. Jan 01, 2015 rotenone rotenone is an odourless, colourless, crystalline ketonic chemical compound used as a broad spectrum insecticide, piscicide, and pesticide. Luckily, there are lots of free and paid tools that can compress a pdf file in just a few easy steps. Rotenone is a mitochondrial electron transport inhibitor, which specifically inhibits nadlinked substrate oxidation of nadh dehydrogenase with an ec5010 pmolmg. Pdf joiner allows you to merge multiple pdf documents and images into a single pdf file, free of charge. Unlike some other pesticides, rotenone is not environmentally persistent and degrades rapidly under natural.
The product is not classified as dangerous according to osha 29 cfr 1910. Rotenone is highly lipophilic and easily crosses the bloodbrain barrier talpade et al. By michelle rae uy 24 january 2020 knowing how to combine pdf files isnt reserved. Depending on the type of scanner you have, you might only be able to scan one page of a document at a time. Although no longer offered for sale in the usa as a pesticide, rotenone is still in use in other countries. Rotenone degradation is highly accelerated in alkaline soils. Msds document numbern000 revision dated 03 sept 96 in an emergency, call chemtrec at 8004249300 us toll free or 7035273887 contents. National organic standards board proposal to add rotenone.
Rotenone absorption by the gut is limited in mammals therefore rotenone is mainly only toxic when injected into a vein pubchem, n. In soil, rotenone is readily degraded by hydrolysis and microbial action. Rotenone is derived from the roots and stems of certain tropical and subtropical plants. In vitro, this compound also activates microglial superoxide release, resulting in neurodegeneration of dopaminergic neurons, mimicking pathologies associated with parkinsons disease. Rotenone is the trivial name of the main chemical component of certain plants of the derris, lonchocarpus, tephrosia and mundulea species. Rotenone is a rotenoid plant extract obtained from such species as barbasco, cub, haiari, nekoe, and timbo. Proposed activities rotenone is a naturally occurring substance derived from the roots of tropical plants in the bean family.
This product is not considered to be known or suspected human carcinogen by ntp, iarc or osha see section 3. Substance and source identification product identifier srm. Rotenone cas 83794 order from adipogen life sciences. Only select registry of toxic effects of chemical substances rtecs data is presented here. An oversized pdf file can be hard to send through email and may not upload onto certain file managers. A pdf file is a portable document format file, developed by adobe systems. Trade names for products containing rotenone include chemfish, cuberol, fish tox, noxfire, rotacide, sinid and toxr. Alternatively, search the catalog for a product and then the sds link on the right side under about this product. Material safety data sheet msds information and applicability the material safety data sheet msds requirements of the occupational safety and health administration osha for chemicals are not applicable to manufactured articles such as lamps. Searching for a specific type of document on the internet is sometimes like looking for a needle in a haystack. The msds for both powdered and liquid rotenone formulations indicates that inhalation can be fatal. Although there is no requirement to keep the older msds once it is replaced with an sds, a good management practice would be to keep an electronic copy on file, especially if existing stocks of the chemical were purchased under the older msds. Helium msds material safety data sheet for helium he reference.
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